What is Replicine?

Popping up now and then in the discussion about natural keratin proteins is the word ‘Replicine’.  I want to talk a little today about what exactly Replicine is and what it means when you find it on your ingredient list.

First things first, what on earth is Replicine?

You can think of it almost as a brand of functional keratin protein.  Are you wondering how protein can be branded?  It’s all about the patent.

See, Replicine is a fully functional keratin protein that has been extracted from pure New Zealand wool. Replicine is the only commercially available keratin protein that has been extracted using this patented technology.  So if you’ve got any sort of functional keratin in your hair product, you can bet it’s Replicine.

What exactly makes Replicine keratin technology different to other keratins?  Replicine respects the complexity of natural proteins and works to replicate them in form, sequence and function.  Remember the post about hydrolyzed keratin?  We all know by now why hydrolyzed keratin just doesn’t cut it in terms of giving your hair the full benefits of keratin.

Replicine, on the other hand, acts just like the natural keratin in your hair and gives you all the same protection and strength. I’ll explain how this works.

Replicine understands nature’s complexity

Most labs treat all keratins as the same, but the scientists behind Replicine know that this is not the case.  Rather, keratins can be categorized into families.  Some keratin families are responsible for strength and some act more as glue that holds the hair together.

By respecting the different forms of keratin, Replicine functional keratin technology can isolate and use the proteins exactly how they were intended to be used.  For instance, in hair products, Replicine is the only keratin protein that can mimic and can regenerate with your own hairs natural keratin.

Replicine maintain keratin’s form and function

Imagine a zipper.  The teeth on both sides need to be designed to perfectly fit and lock into each other.  If the spaces or the sizes aren’t perfectly matched to each other, then the zipper doesn’t work.

Keratin can be thought of like a zipper.  You want the keratin in your hair and skincare products to interact with the natural keratin in your body.  So picture the teeth of one side of the zipper as your own natural keratin.  What should the teeth on the other side look like?

Well, if you want the zipper to work the teeth need to be exactly the same on both sides.  That’s why Replicine completely replicates the form of natural keratin proteins.  So it fits right in with the stuff in your hair and skin.

Replicine controls sulphur amino acids

Making up about 5% of your hair is an amino acid called cystine.  Cystine determines the structure of proteins by forming bonds between and within protein molecules.

We already know that the structure of the proteins is crucial to their function, so clearly the cystine in the keratin plays an important role.  Unfortunately, few companies seem to realize this and cystine is almost always destroyed in the extraction process.

Replicine makes sure the amino acids in keratin is protected to keep the cystine intact and ensure that it can bind to the hair like it’s supposed to.

And that’s Replicine!

All of these things go into the extraction and processing of keratin from pure New Zealand sheep’s wool to result in Replicine.  Each of these processes, by the way, is patented by a company called Keraplast.  Keraplast is the only holder of these technologies and Replicine is the only protein that can claim them.

So there’s your science lesson for the day.  Just remember to check the ingredient list before you buy your keratin product…  Look for Replicine, the only fully-functioning keratin protein on the market.

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14 Responses to What is Replicine?

  1. Oscar on

    I am a french student working on keratin for my major in science.
    For now, I have almost everything I need, but I NEVER found anything on the “keratin” that exist on the hair extensions (keratin tips as it is called).
    I found your email after working on this in many forums and web sites.

    Do you have any information on this thing? I don’t think it is real keratin, but I would like to have some place in my memoir for this kind of products.

    Thank you in advance for your time,

    • Keratin Questions on

      Hi Oscar,
      I’m sorry but I don’t know a lot about the glue used in hair extensions. There are a few on the market and they will have differences in their formulations. Some are based on a combination of rubber latex and sodium polyacrylate, others are a polyamide, but this may not be the case with all hair extension glues. However generally speaking the glue is unlikely to be a keratin based compound. Depending on how they have been processed, Keratins are either water soluble or completely insoluble, whereas the glue used can be dissolved using acetone. This suggests some sort of rubber or petrochemical based adhesive. It is possible that there may be some hydrolyzed keratin incorporated into the adhesive formulation, but this would not be providing the durable adhesion that these products have. You can have a look at this site where they claim to have assessed a number of top brand keratin extension adhesives and found none of them to contain keratin

      But to add to the information contained on the site given above: unlike most sources of keratin, the patented process used to manufacture Replicine™ Functional Keratin® is the ONLY commercial process capable of extracting the keratin proteins out of the keratin fiber, without damaging them. In this process healthy New Zealand sheep wool is used as the source of the keratin and this is very similar to human hair keratin. At this stage, Replicine is not used in glues for hair extensions.

  2. Michelle on

    My auntie owns a salon in London and she is interested in sampling your range. How does she go about arranging that? Also is replicine edible? I have seen a company from New Zealand selling a supplement which they claim has the sheeps wool keratin.
    Is this plausible and safe?

    Thank you

    • Keratin Questions on

      Hi Michelle,

      Thank you very much for that referral. Keraplast will get in touch with you directly to organize to send samples to your aunt.

      Depending on how it is processed- yes keratin from NZ wool is edible and safe. There are several products on the market available that include keratin from New Zealand wool. The Finest Nutrition line sold in in the American retailer Walgreens is one of them. There are also the Younger Secrets Marine Keratin and Collagen formula capsules that your link goes to. The following products include edible keratin from NZ sheep wool:

      – Dr. Susan Lark Hair & Nails Revitalizer
      – ResVitále™ Keratin Enhance
      – Futurebiotics Hair, Skin & Nails® Intense Therapy
      – Supersmart.com hair and Nails Formula
      – Lorica Kera-Concept
      – Nasstassja Ultra NHS
      – Douglas Laboratories Ultra NHS

      When processed in the correct way then keratin from New Zealand wool can provide significant benefits in hair, skin and nail health as well as for joint health. Here are some scientific publications that describe the benefits.


  3. Kerry on

    Our company has recently launched a skin care range, being a hair salon owner as well I would like to develop our own keratin protein treatment. Would I be able to buy Replicine to use in our own products?

    • Keratin Questions on

      Hi Kerry,
      Keraplast does offer private label for hair care. We will be in touch with you directly to discuss this further.

  4. Dawn on


    I am a wavy haired gal that constantly gets comments from co-worker that I need to get a Brazilian blow out due to the frizziness of my locks. I don’t want straight hair, but I would love to tame the frizz. I most often just wash, mousse/gel and go, but sometimes I can get to the blow dryer and tools. Can you direct me where I might find some sample sizes of your product to try?

    • Keratin Questions on

      Hi Dawn,
      Keraplast has a product called Hair Rescue. It is an intensive repair treatment that helps to restore dry, frizzy, chemically damaged hair back to a healthy, shiny state. We will be in contact you directly in obtaining product.

  5. sarah on

    I am biotech student and would like to know after extraction how you prove that your product is keratin. Do you have special protein test for keratin? Also what test do you have for improvement of keratin effects on hair and skin?

    • Keratin Questions on

      Hi Sarah,
      Thanks for your questions!
      The Keraplast processes start with cleaned New Zealand sheep wool, which is more than 80% keratins. The remainder is water (16-18%) and a small amount of internal and external wool lipids and cell membranes (about 1-2%). There is a large body of published research from Research Organizations, WRONZ (New Zealand) and CSIRO (Australia), that verifies this information.
      The extraction processes are water-based so as to solubilize the keratins. The lipids are water insoluble and are left behind with the residue which contains some of the more intractable proteins and cell membranes.
      Keraplast have validated that they are extracting keratins using a number of laboratory techniques including 1- and 2- dimensional electrophoresis (IEF and SDS-PAGE), size chromatography and also mass chromatography.
      Regarding measurements of hair strength and other properties- Keraplast has multiple single fiber testing undertaken with treated and untreated tresses using an Instrom Tensile tester, and they use combing procedures to determine hair breakage. Keraplast also has an independent researcher undertake sensorial testing with a panel of hair stylists for sensorial and visual properties.
      For skin; Keraplast have undertaken skin trials with finished formulations with and without the keratins, and measured various skin properties such as hydration, trans-epidermal water loss (TEWL), elasticity and erythema.
      For more information please see Keraplast’s comprehensive list of publications at: http://www.keraplast.com/scientific-publications

  6. Isabella on

    I just got my keratin treatment done on Wednesday but I was wondering if we are allowed to curl our hair with a curling wand or iron? I like to change up my hair style once in a while.

    • Keratin Questions on

      Hi Isabella,
      If your treatment was done professionally, it is always best to check with the salon before doing anything to the hair to ensure the length of your keratin treatment.
      Using a sulfate, sodium free shampoo and shampooing less will help to keep the desired results of the treatment. Typically keratin treatments have a three day waiting period, no washing, sweating, use of heat, or disturbing the hair in anyway.
      After the waiting period is over, professionals say it is safe to curl the hair.

  7. Brie on

    Hello. My name is Brie and I’m currently developing a line of hair care products that naturally stimulate hair growth. My question is simple. If I incorporate keratin into my products, how much should I use in each product and how much of an impact would it have on the rate of growth in comparison to not including keratin in the formula?

    • Keratin Questions on

      Hi Brie,
      Thanks for your question! I am not aware of published research that has quantified an improvement in hair growth using keratin compared with not using keratin. However there is both published and unpublished work that shows significant improvement to hair strength, and reduction in the loss of hair from combing, resulting from using keratin containing formulations. This is both through ingestible products (ie tablets or capsule supplements) and topical products (shampoos, conditioners etc).
      For published work, with keratins in liquid formulations (conditioner etc) please see:

      • A Roddick-Lanzilotta, , R. Kelly, S. Scott and S. Chahal (2007). New keratin isolates: Actives for natural hair protection. J Cosmet Sci 58(4): 405-411
      • C Barba, S Scott, A D Roddick-Lanzilotta, R J Kelly, A M Manich, L Coderch, J L Parra (2010), Restoring Important Hair Properties with Wool Keratin Proteins and Peptides, Fibers and Polymers (2010), Vol.11, No.7, 1055-1061
      • G Worth, R Kelly, G Krsinic, S Scott and A Roddick-Lanzilotta (2015) Investigating Oxidized Keratin in Repair of Hair Personal Care Magazine 2015, November 33-38

      Please also be aware that not all keratins are the same; the information presented here all relates to keratin peptides and proteins that have been generated from sheep wool via the Keraplast proprietary processes.
      To find out further information on other unpublished data, I suggest that you contact the suppliers of these ingredients directly:
      For Keratins proteins and peptides suitable for haircare liquid products please contact Keraplast at http://www.keraplast.com/contact
      For Keratin suitable for tablets and capsules please contact Roxlor at http://www.roxlor.com/contact.php

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